- Scientists use CRISPR to delete CCR5 gene (providing immunity to HIV) in single patient - study failed to control infection (attributable to low DNA edit rates), but was safe (no unintended genetic alterations were observed) - this therapy made DNA edits in adult cells (can't be passed to next gen) https://www.nejm.org/doi/full/10.1056/nejmoa1817426?query=featured_home 5 comments science
Linking pages
- Chinese scientists use CRISPR tool on HIV patient for the first time | CNN https://www.cnn.com/2019/09/13/health/china-crispr-hiv-intl-hnk/index.html 61 comments
- Chinese Scientists Try to Cure One Man's HIV With Crispr | WIRED https://www.wired.com/story/chinese-scientists-try-to-cure-one-mans-hiv-with-crispr/ 0 comments
Linked pages
- Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2208375 145 comments
- Intermittently Scanned Continuous Glucose Monitoring for Type 1 Diabetes | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2205650 3 comments
- Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV | NEJM http://www.nejm.org/doi/full/10.1056/NEJMoa1300662 0 comments
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