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- Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection http://www.nejm.org/doi/full/10.1056/NEJMoa1702090?query=featured_home 35 comments
- Oscar the Cat: Can Reliably Detect Impending Death http://www.nejm.org/doi/full/10.1056/NEJMp078108#t=article 2 comments
- HIV-1 Remission after Allogeneic Hematopoietic-Cell Transplantation https://www.nejm.org/doi/full/10.1056/NEJMc2312556 9 comments science
- Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2310392?query=featured_home 2 comments science
- In a clinical trial of adults older than 55, bivalent omicron BA.1–adapted BNT162b2 had a safety profile similar to that of BNT162b2 (30 μg), induced substantial neutralizing responses against ancestral and omicron BA.1 strains, and, to a lesser extent, neutralized BA.4, BA.5, and BA.2.75 strains. https://www.nejm.org/doi/full/10.1056/NEJMoa2213082 5 comments science
- For the first time in history , an experimental cancer drug had a 100 % success rate in a very small clinical trial in the U.S. 12 patients took a drug called Dostarlimab for around six months only to find that their cancer has disappeared , according to a study published in The New England Journal https://www.nejm.org/doi/pdf/10.1056/NEJMoa2201445 3 comments science
- COVID vaccination of children age 5-11 cut Omicron hospitalizations by 68%. Of children ages 5-11 hospitalized with COVID-19, 92 percent were unvaccinated. Sixteen percent were critically ill, needing life support measures such as intubation. Of these, 90 percent were unvaccinated. https://www.nejm.org/doi/full/10.1056/NEJMoa2202826 21 comments science
- Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2109908 6 comments science
- Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2109522 5 comments science
- SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia https://www.nejm.org/doi/full/10.1056/nejme2106315?query=rp 7 comments science
- SARS-CoV-2 Infection after Vaccination in Health Care Workers in California https://www.nejm.org/doi/full/10.1056/nejmc2101927? 10 comments science
- CRISPR-Cas9 gene editing successful for a patient with Sickle Cell Disease and another patient with transfusion dependent β-Thalassemia - More than a year later, both patients had clinically improved and no longer needed blood transfusions. (NEJM, 5 Dec 2020) https://www.nejm.org/doi/full/10.1056/nejmoa2031054 461 comments science
- A scientific journal explains Why a GME Squeeze Is Unlikely https://www.nejm.org/doi/full/10.1056/NEJMp1511707 10 comments wallstreetbets
- NEJM: Covid-19 has created a crisis throughout the world. This crisis has produced a test of leadership. With no good options to combat a novel pathogen, countries were forced to make hard choices about how to respond. Here in the United States, our leaders have failed that test. https://www.nejm.org/doi/full/10.1056/nejme2029812?query=featured_home 44 comments science
- Dying in a Leadership Vacuum https://www.nejm.org/doi/full/10.1056/nejme2029812 3 comments politics
- Large review of studies comparing placebo treatment to no treatment finds little evidence of "placebo effect" for objective outcomes compared to no treatment https://www.nejm.org/doi/full/10.1056/nejm200105243442106 23 comments science
- Facial Masking for Covid-19 — Potential for “Variolation” as We Await a Vaccine https://www.nejm.org/doi/full/10.1056/nejmp2026913 4 comments science
- Most advanced mRNA Vaccine against SARS-CoV-2 produced robust immune response in all patients https://www.nejm.org/doi/full/10.1056/nejmoa2022483 1291 comments science
- In Pursuit of PPE https://www.nejm.org/doi/full/10.1056/nejmc2010025?utm_source=fark&utm_medium=website&utm_content=link&icid=ref_fark 3 comments politics
- Washington 2019-nCoV Patient Treated with Experimental Antiviral Drug, Remdesivir https://www.nejm.org/doi/10.1056/nejmoa2001191 4 comments worldnews
- Study provides strong evidence that regions with lower exposures to particulate air pollution (PM2.5 and PM10) had higher per-unit health risks — meaning that countries with relatively good air quality (like the US) could see significant public health benefits from additional clean air regulations. https://www.nejm.org/doi/full/10.1056/nejme1909053 4 comments science
- A new study published Wednesday in the New England Journal of Medicine found that 1-in-4 individuals, globally, will have a stroke at age 25 or older. The risk of stroke from the age of 25 onward was 24.9%, up from 22.8% in 1990. This includes risk of first-time, ischemic, and hemorrhagic strokes. https://www.nejm.org/doi/full/10.1056/nejmoa1804492?query=featured_home 6 comments science
- “During an extreme bout of coughing, the patient spontaneously expectorated an intact cast of the right bronchial tree. “ https://www.nejm.org/doi/full/10.1056/nejmicm1806493 37 comments science
- ADHD diagnosis is associated with an August birthday, but only in states with a Sept 1 cutoff for kindergarten https://www.nejm.org/doi/pdf/10.1056/nejmoa1806828 214 comments science
- Supplementation with n−3 fatty acids did not result in a lower incidence of major cardiovascular events or cancer than placebo. https://www.nejm.org/doi/full/10.1056/nejmoa1811403 15 comments science
- Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer https://www.nejm.org/doi/full/10.1056/nejmoa1811403?query=rp 5 comments science
- Obesity onset occurs early in life, with the greatest excessive weight gain occurring between 2 and 6 years of age, and once it develops, it persists into adolescence - NEJM https://www.nejm.org/doi/full/10.1056/nejmoa1803527 15 comments science
- Effect of aspirin on all-cause mortality in the healthy elderly: despite reductions in cardiovascular-related, higher all-cause mortality was observed deaths primarily due to increased cancer-related deaths. https://www.nejm.org/doi/full/10.1056/nejmoa1803955?query=featured_home 4 comments science
- Postpartum hemorrhage is the most common cause of maternal death. The standard treatment must be held in cold storage, making it unavailable in many developing nations. Scientists identified a new, heat-stable treatment that’s just as good, spurring hope that it could save many lives. https://www.nejm.org/doi/full/10.1056/nejmoa1805489?query=gynecology-obstetrics 317 comments science
- President Trump’s Mental Health — Is It Morally Permissible for Psychiatrists to Comment? http://www.nejm.org/doi/full/10.1056/nejmp1714828 68 comments politics
- Landmark Phase 3 Trial finds novel drug Olaparib more effective for Metastatic Breast Cancer in BRCA patients than Current Treatment — NEJM http://www.nejm.org/doi/full/10.1056/nejmoa1706450?query=featured_home 3 comments science
- An innovative new drug, Evolocumab, can prevent heart attacks and strokes by cutting bad cholesterol to unprecedented levels on a background of statin therapy, in a large randomized, double-blind, placebo-controlled trial involving 27,564 patients published in the NEJM. http://www.nejm.org/doi/full/10.1056/nejmoa1615664 33 comments science
- Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils http://www.nejm.org/doi/full/10.1056/nejmoa064725#t=articletop 7 comments science
- Scientists just documented the first case of Zika spreading through physical contact http://www.nejm.org/doi/full/10.1056/nejmc1610613?query=featured_home& 227 comments science
- NEJM study: Zika virus associated with microcelaphy http://www.nejm.org/doi/full/10.1056/nejmoa1600651# 10 comments science
- Two kids with a mutation in the gene encoding MOGS (a protein which processes glycans during protein glycosolation) are found to be immune to many viruses including influenza, herpes, dengue fever, hepatitis C, and HIV. http://www.nejm.org/doi/full/10.1056/nejmoa1302846#t=article 699 comments science
- Cytomegalovirus DNA detected in 249/250 tested glioblastoma tumors (brain tumor). Anti-viral drug valganciclovir improves 2 year survival 3.4 fold over control (P<0.001). http://www.nejm.org/doi/full/10.1056/nejmc1302145 3 comments science
- Poop is more effective at treating intestinal infections than antibiotics. http://www.nejm.org/doi/full/10.1056/nejmoa1205037 50 comments science
- Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children http://www.nejm.org/doi/full/10.1056/nejmoa1200850?query=featured_home 5 comments science
- The Beginning of the End of AIDS? http://www.nejm.org/doi/full/10.1056/nejmp1207138?query=featured_home 9 comments science