Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation

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AAV5–Factor VIII Gene Transfer in Severe Hemophilia A | NEJM http://www.nejm.org/doi/full/10.1056/NEJMoa1708483?query=featured_home 55 comments
Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2200797 43 comments
Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2104983 38 comments
Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2110475 35 comments
A Bivalent Omicron-Containing Booster Vaccine against Covid-19 | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2208343 33 comments
Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2027540 22 comments
Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections | NEJM https://doi.org/10.1056/NEJMoa2203965 15 comments
Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox | NEJM https://www.nejm.org/doi/full/10.1056/nejmoa1817307 14 comments
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2107454?query=featured_home 11 comments
The Oregon Experiment — Effects of Medicaid on Clinical Outcomes | NEJM http://www.nejm.org/doi/full/10.1056/NEJMsa1212321#t=articleTop 10 comments
10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer | NEJM http://www.nejm.org/doi/full/10.1056/nejmoa1606220?query=toc 8 comments
Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer | NEJM http://www.nejm.org/doi/full/10.1056/nejmoa1701717?query=featured_home 7 comments
Vaccine Breakthrough Infections with SARS-CoV-2 Variants | NEJM https://www.nejm.org/doi/full/10.1056/nejmoa2105000?query=featured_home 6 comments
Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer | NEJM http://www.nejm.org/doi/full/10.1056/nejmoa1708423?query=featured_home 5 comments
Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2110275 5 comments
Handgun Ownership and Suicide in California | NEJM https://doi.org/10.1056/nejmsa1916744 4 comments
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2204919 1 comment