Hacker News
- Proteins central to the pathology of Alzheimer’s disease act as prions – study https://www.ucsf.edu/news/2019/05/414326/alzheimers-disease-double-prion-disorder-study-shows 103 comments
- Avoiding Alzheimer’s Disease Could Be Easier Than You Think https://www.psychologytoday.com/us/blog/diagnosis-diet/201609/avoiding-alzheimer-s-disease-could-be-easier-you-think 10 comments
- Scientists Discover a Potential Way to Repair Synapses Damaged in Alzheimer’s Disease https://www.buckinstitute.org/news/buck-scientists-discover-a-potential-way-to-repair-synapses-damaged-in-alzheimers-disease/ 2 comments science
- AI that reads brain scans shows promise for finding Alzheimer’s genes. Machine-learning approach detects Alzheimer’s disease with an accuracy of more than 90% — a potential boon for clinicians and scientists developing treatments. https://www.nature.com/articles/d41586-023-03482-9 32 comments futurology
- High metabolism is an early sign of Alzheimer’s disease: Researchers now show that a metabolic increase in the mitochondria, the cellular power plants, is an early indicator of the disease. The teams behind the study used mice that developed Alzheimer’s disease pathology in a similar way to humans. https://www.nature.com/articles/s41380-023-02289-4 2 comments science
- Boosting Neuron Formation Restores Memory in Mice With Alzheimer’s Disease https://neurosciencenews.com/bax-alzheimers-neurogenesis-21266/ 16 comments futurology
- Reprogramming the Brain’s Cleaning Crew to Mop Up Alzheimer’s Disease Scientists pinpointed genes that effect the cell's ability to survive and proliferate, how actively a cell produces inflammatory substances, and how aggressively a cell prunes synapses. https://www.ucsf.edu/news/2022/08/423446/reprogramming-brains-cleaning-crew-mop-alzheimers-disease 5 comments science
- Early Alzheimer’s detection up to 17 years in advance. A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity. https://news.rub.de/english/press-releases/2022-07-21-biology-early-alzheimers-detection-17-years-advance 1519 comments science
- Potential fabrication in research images threatens key theory of Alzheimer’s disease https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease 59 comments technews
- Investigating the Role of Spermidine in a Model System of Alzheimer’s Disease Using Correlative Microscopy and Super-resolution Techniques (2022) https://www.frontiersin.org/articles/10.3389/fcell.2022.819571/full 4 comments science
- Midlife lipid and glucose levels are associated with Alzheimer's disease — A 15 mg/dL increase in glucose measured during middle adulthood was associated with 14.5% increased AD risk https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12641 25 comments science
- The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to new research. The research underscores the importance of healthy sleep habits and opens a path to potential Alzheimer's therapies. https://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1009994 15 comments science
- Cannabinol, an active ingredient in cannabis, can help protect brain cells from oxidative damage & preserve mitochondrial function, two of the major contributors to Alzheimer’s. It could lead to the development of new therapeutics for treating this disease & other neurodegenerative disorders. https://www.sciencedirect.com/science/article/abs/pii/S0891584922000016?via%3Dihub 87 comments science
- Using Viagra could help prevent Alzheimer’s disease developing, a new study shows https://www.euronews.com/next/2021/12/10/using-viagra-could-help-prevent-alzheimer-s-disease-developing-a-new-study-shows 20 comments worldnews
- Cleveland Clinic Research Identifies Sildenafil as Candidate Drug for Alzheimer’s Disease - Findings published in Nature Aging show 69% reduced likelihood of developing the disease https://newsroom.clevelandclinic.org/2021/12/06/cleveland-clinic-research-identifies-sildenafil-as-candidate-drug-for-alzheimers-disease/ 11 comments science
- Personality traits and hallmarks of Alzheimer’s disease. Researchers found personality can help protect against Alzheimer’s and other neurological diseases by delaying or preventing the emergence of neuropathology for those strong in conscientiousness and low in neuroticism. https://news.fsu.edu/news/health-medicine/2021/10/12/fsu-college-of-medicine-research-links-personality-traits-and-hallmarks-of-alzheimers-disease/ 69 comments science
- Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001358 5 comments science
- How we sleep today may forecast when Alzheimer's disease begins. Neuroscientists find way to predict when dementia most likely to strike based on baseline sleep patterns. Study in Current Biology. https://news.berkeley.edu/2020/09/03/how-we-sleep-today-may-forecast-when-alzheimers-disease-begins/ 12 comments science
- The world’s first new drug (Oligomannate) for the treatment of Alzheimer’s disease in nearly 20 years – and perhaps the only treatment with the potential to reverse the condition – was approved by the Chinese government on Saturday night https://www.scmp.com/news/china/science/article/3036119/china-approves-oligomannate-worlds-first-new-alzheimers-drug-20 4 comments science
- Research confirms link between dementia and football. Dr Willie Stewart: "This analysis revealed that risk ranged from a 5-fold increase in Alzheimer’s disease, an approximately 4-fold increase in motor neurone disease, to a 2-fold Parkinson’s disease in former professional players" https://twitter.com/JWTelegraph/status/1186236610146422785 153 comments soccer
- Alzheimer's disease destroys neurons that keep us awake. https://www.eurekalert.org/pub_releases/2019-08/uoc--add080719.php 4 comments science
- Millions of elderly people have a form of dementia that has been misdiagnosed as Alzheimer's disease, according to researchers. One expert called it the most important dementia finding in years. https://www.bbc.com/news/health-48092570 23 comments worldnews
- Gum disease may be the cause of Alzheimers https://www.newscientist.com/article/2191842-gum-disease-may-be-the-cause-of-alzheimers-heres-how-to-avoid-it/ 5 comments science
- A bacteria that commonly causes gum infections also seems to be causing Alzheimer's. Many scientists suspected the disease was caused by a bacterial infection, and when scientists gave P. gingivalis to mice, the rodents developed memory loss and amyloid beta plaque. A treatment is now being tested. http://blogs.discovermagazine.com/d-brief/2019/01/23/dental-infection-may-spur-alzheimers-disease/#.xekbfc9khty 90 comments science
- How does a disease like alzheimers or Parkinsons kill you? https://www.reddit.com/r/askscience/comments/acd4zu/how_does_a_disease_like_alzheimers_or_parkinsons/ 5 comments askscience
- Up to 50% of people with pathological signs of Alzheimer's disease do not develop dementia. This has prompted a search for mechanisms of cognitive resilience. A new study shows that dendritic spines provide such resistance, suggesting that targeting dendritic spine plasticity may ameliorate AD. http://onlinelibrary.wiley.com/doi/10.1002/ana.25049/full 6 comments science
- This AI system can detect Alzheimer's disease nearly a decade before symptoms appear http://www.ibtimes.co.uk/this-ai-system-can-detect-alzheimers-disease-nearly-decade-before-symptoms-appear-1639727 12 comments technology
- Genes associated with Alzheimer's, coronary artery disease, and asthma are selected against in humans http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002458 16 comments science
- Long-winded speech could be early sign of Alzheimer's disease, says study https://www.theguardian.com/society/2017/feb/21/long-winded-speech-could-be-early-sign-of-alzheimers-says-study 3 comments science
- Alzheimer's disease breakthrough as new drug clears toxic proteins from brains of patients http://www.independent.co.uk/news/science/alzheimers-disease-dementia-breakthrough-new-drug-scientists-a7218481.html 1545 comments worldnews
- Fungal infection in patients with Alzheimer's disease. http://www.ncbi.nlm.nih.gov/pubmed/24614898 3 comments science
- 15-year-old schoolboy develops test for Alzheimer's disease http://www.telegraph.co.uk/news/science/science-news/11734666/15-year-old-schoolboy-develops-test-for-alzheimers-disease.html 9 comments science
- Common medications linked to dementia, Alzheimer's disease, study finds http://s.oregonlive.com/odsi1ji 29 comments science
- New non-invasive method can detect Alzheimer's disease at the earliest stages of the disease, well before typical Alzheimer's symptoms appear. http://www.eurekalert.org/pub_releases/2014-12/nu-nnm122214.php 6 comments science
- Has Stanford University found a cure for Alzheimer's disease? - Telegraph http://www.telegraph.co.uk/news/science/science-news/11280504/has-stanford-university-found-a-cure-for-alzheimers-disease.html 11 comments science
- Funding for Alzheimer’s disease (AD) :: $122 million. Good enough? http://www.science4everyone.com/2014/01/congress-gets-it-right-finally-well-maybe-not/ 4 comments science
- Mystery Ingredient in Coffee Boosts Protection Against Alzheimer's Disease (x-post from r/coffee) http://www.sciencedaily.com/releases/2011/06/110621093301.htm 4 comments science
- A molecular link between the active component of marijuana and Alzheimer's disease pathology. http://www.ncbi.nlm.nih.gov/pubmed/17140265 421 comments science
- A breakthrough discovery by scientists from the Mayo Clinic may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques — considered a hallmark of the disease — from patients' brains. http://www.sciencedaily.com/releases/2009/10/091015091602.htm 4 comments reddit.com
- Is this Ironic? The Conservative Ronald Reagan took away health care for the mentally ill only to develop Alzheimer disease. http://video.google.com/videosearch?q=reagan%20it%20was%20carters%20fault&oe=utf-8&rls=com.ubuntu:en-us:unofficial&client=firefox-a&um=1&ie=utf-8&sa=n&hl=en&tab=wv#q=ronald+reagan&hl=en&emb=0&client=firefox-a 3 comments politics