- Largest study on aging in human skeletal muscle to date finds that mitochondrial dysfunction is a major age-related factor and highlights the beneficial effects of maintaining a high physical capacity for prevention of age-related sarcopenia. http://www.skeletalmusclejournal.com/content/5/1/35 25 comments science
- Myostatin may contribute to the higher prevalence of sarcopenia in women but acts as a homeostatic regulator of muscle mass in men. http://www.skeletalmusclejournal.com/content/5/1/21 3 comments science
- Aging is associated with both a selective loss of fast-type skeletal muscle fibers and decreases in the robustness of the molecular clock. These new observations raise the possibility that fast to slow fiber-type shifts may be a result of dampening of the molecular clock with age. http://www.skeletalmusclejournal.com/content/5/1/17 660 comments science