- Using opioids for chronic pain can paradoxically result in higher pain in some people, leading to increased tolerance and physical/mental dependence. A new study in mice reveals that serotonin may play a key role in this effect, and may be a therapeutic target for opioid-induced hyperalgesia. https://www.jpain.org/article/S1526-5900(21)00004-3/fulltext 12 comments science
- Gender Biases in Estimation of Others’ Pain https://www.jpain.org/article/s1526-5900(21)00035-3/fulltext 8 comments science
- New study confirms that paced breathing can reduce pain. Pain relief benefits were especially strong when breathing was slow, and when exhalation was longer than inhalation. https://www.jpain.org/article/s1526-5900(20)30002-x/fulltext 36 comments science
- Inhaled cannabis reduces self-reported headache and migraine severity by approximately 50%, based on a medical cannabis app study. However, its effectiveness diminish and patients appear to use larger doses across time, suggesting tolerance to these effects may develop with continued use. https://www.jpain.org/article/s1526-5900(19)30848-x/fulltext 611 comments science
- Acupuncture has a clinically relevant, persistent effect on chronic pain that is not completely explained by placebo effects. Referral for acupuncture is a reasonable option for chronic pain. | The Journal of Pain - May 2018 https://www.jpain.org/article/s1526-5900(17)30780-0/fulltext 67 comments science
- Study finds that alcohol is as effective as opioids at reducing pain: a new meta-analysis found that people with a blood alcohol content of .08% had moderate-to-large reductions in pain intensity, comparable to pain relief from opioids http://www.jpain.org/article/s1526-5900(16)30334-0/fulltext 44 comments science
- Study finds that alcohol is as effective as opioids at reducing pain; a new meta-analysis found that people with a blood alcohol content of .08% had moderate-to-large reductions in pain intensity, comparable to pain relief from opioids http://www.jpain.org/article/s1526-5900(16)30334-0/fulltext 4 comments science
- Individuals with complex regional pain syndrome experience pain simply by watching other people's movements. http://www.jpain.org/article/s1526-5900(16)30309-1/abstract 6 comments science