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- mRNA vaccines highly effective at preventing death, less at preventing infection https://www.acpjournals.org/doi/10.7326/M21-3256 5 comments
- Effectiveness of Mask Recommendation to Prevent SARS-CoV-2 (Randomized trial) https://www.acpjournals.org/doi/10.7326/M20-6817 25 comments
- Low dose Vitamin D and Calcium supplementation study didn’t show lower risk of hip fracture in post menopausal women, but did show decreased risk mortality and increased risk heart disease https://www.acpjournals.org/doi/10.7326/M23-2598 23 comments science
- 20% of people experienced Covid viral rebound in this Observational study of Paxlovid from November 2023. https://www.acpjournals.org/doi/10.7326/M23-1756 12 comments science
- Trends in Psychological Distress and Outpatient Mental Health Care of Adults During the COVID-19 Era https://www.acpjournals.org/doi/abs/10.7326/M23-2824 3 comments science
- In the US for people who survive gunshot wounds, the trauma may leave mental scars that worsen with time. Among 87 adults treated for gun injuries at a Wisconsin trauma center, many had worsening symptoms of post-traumatic stress disorder (PTSD) and depression six months later. https://www.acpjournals.org/doi/10.7326/M23-0309 72 comments science
- Research found that vitamin D supplements were modestly effective in curbing the risk of pre-diabetes progressing to Type 2 diabetes. Over three years, just under 23% of study patients using vitamin D developed diabetes, versus 25% of those given placebo pills. https://www.acpjournals.org/doi/10.7326/M22-3018 26 comments science
- Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial -- LCHF diet had greater improvements in hemoglobin A1 and weight loss https://www.acpjournals.org/doi/10.7326/M22-1787 85 comments science
- Vitamin D deficiency linked to premature death. Over a 14-year follow up period, researchers found that the risk for death significantly decreased with increased vitamin D concentrations, with the strongest effects seen among those with severe deficiencies. https://www.acpjournals.org/doi/10.7326/M21-3324 155 comments science
- Cohort study (n=17,569,096) finds living with a handgun owner is associated with substantially elevated risk for dying by homicide and women are disproportionately affected. https://www.acpjournals.org/doi/full/10.7326/M21-3762 11 comments science
- Number of medical cannabis patients more than quadrupled by 2020 from 2016 https://www.acpjournals.org/doi/10.7326/M22-0217 16 comments science
- Homicide Deaths Among Adult Cohabitants of Handgun Owners in California, 2004 to 2016 | Overall rates of homicide were more than twice as high among cohabitants of handgun owners than among cohabitants of nonowners https://www.acpjournals.org/doi/full/10.7326/M21-3762 85 comments science
- New Study Finds Cannabis Products Provide Short-Term Reduction in Chronic Pain; More Research Needed on Long-Term Effects https://www.acpjournals.org/doi/10.7326/M21-4520 11 comments science
- Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality: A Large Prospective Cohort Study: Annals of Internal Medicine: Vol 0, No 0 https://www.acpjournals.org/doi/10.7326/M21-2977 3 comments science
- A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings | Annals of Internal Medicine https://www.acpjournals.org/doi/10.7326/M21-4905 3 comments science
- Initial results from an NIH cohort study on postacute sequelae of SARS-CoV-2 infection (PASC, i.e. "long COVID") found few differences between COVID-19 survivors and control participants in objective tests, such as physical examination, neurocognitive assessment, and plasma inflammatory biomarkers. https://www.acpjournals.org/doi/10.7326/M21-4905 5 comments science
- Gun violence can cause significant, long-lasting mental harm to survivors and their families. In the year after being shot, survivors had a 40% rise in pain diagnoses, a 51% rise in mental health conditions, and an 85% increase in substance use disorders, compared with other patients. https://www.acpjournals.org/doi/10.7326/M21-2812 17 comments science
- An often overlooked, highly curable cause of high-blood pressure https://www.acpjournals.org/doi/10.7326/m20-0065 4 comments science
- Increased Risk of Carditis After COVID-19 Vaccination With a Messenger RNA Vaccine and an Inactivated Virus Vaccine https://www.acpjournals.org/doi/10.7326/M21-3700 297 comments science
- Chronic pain patients who attended cognitive behavioral therapy in primary care had lower pain, less pain-related disability, and reduced usage of benzodiazepines, but not reduced opioid usage. https://www.acpjournals.org/doi/10.7326/M21-1436 35 comments science
- Consuming alcohol - even one can of beer - can quickly increase the risk of a common type of cardiac arrhythmia known as atrial fibrillation in people https://www.acpjournals.org/doi/10.7326/m21-0228 79 comments science
- The Case for Mandating COVID-19 Vaccines for Health Care Workers https://www.acpjournals.org/doi/10.7326/M21-2366 7 comments worldnews
- Americans living with HIV have the same life expectancy as those without. Suicide rates, however, remain high. https://www.acpjournals.org/doi/10.7326/M21-0065 91 comments science
- Testosterone Therapy Reduces Glucose Intolerance in Men - ACP Journal https://www.acpjournals.org/doi/10.7326/ACPJ202105180-054 9 comments science
- Hospital outbreak of COVID-19 in 14 patients and 38 employees linked back to 1 patient who initially tested negative https://www.acpjournals.org/doi/10.7326/m20-7567 9 comments science
- The combined effectiveness of three COVID-prevention strategies on college campuses — mask-wearing, social distancing, and routine testing — are as effective in preventing coronavirus infections as the vaccines. A combination of these measures costs only $170 per infection prevented. https://www.acpjournals.org/doi/full/10.7326/m20-6558 3 comments science
- Extensive social distancing with a mandatory mask-wearing policy can prevent most COVID-19 cases on college campuses and is very cost-effective. Extensive social distancing with masks cost $170 per infection prevented ($49,200 per QALY) compared with masks alone. https://www.acpjournals.org/doi/10.7326/m20-6558 2 comments science
- The Accessibility of Firearms and Risk for Suicide and Homicide Victimization Among Household Members: A Systematic Review and Meta-analysis: Annals of Internal Medicine: Vol 160, No 2 https://www.acpjournals.org/doi/10.7326/m13-1301 13 comments science
- Turmeric More Effective Than Placebo in Treatment of Knee Osteoarthritis https://www.acpjournals.org/doi/pdf/10.7326/m20-0990 38 comments science
- Randomized controlled trial Assess Face Masks for Protection Against COVID-19 Infection https://www.acpjournals.org/doi/10.7326/m20-6817 18 comments science
- Effectiveness of Adding a Mask Recommendation to Other Public Health Measures to Prevent SARS-CoV-2 Infection in Danish Mask Wearers https://www.acpjournals.org/doi/10.7326/m20-6817 40 comments science
- In adults with severe COVID-19, remdesivir compared with placebo probably improves recovery by a large amount (absolute risk difference [ARD] range, 7% to 10%) and may result in a small reduction in mortality (ARD range, -4% to 1%) and a shorter time to recovery or clinical improvement. https://www.acpjournals.org/doi/10.7326/m20-5752 9 comments science
- Study on COVID-19 Infection Fatality Ratios finds that the infection fatality ratio of persons between the ages of 12 and 40 is 0.01%. https://www.acpjournals.org/doi/10.7326/m20-5352?utm_source=24-scientists-determine-death-rate-covid-19-general-population&utm_medium=email&utm_content=published+in+the+annals+of+internal+medicine&utm_campaign=ag& 9 comments science
- Probable Evidence of Fecal Aerosol Transmission of SARS-CoV-2 in a High-Rise Building https://www.acpjournals.org/doi/10.7326/m20-0928 51 comments science
- Obesity plays a profound role in risk for death from COVID-19, particularly in male patients and younger populations.Compared with patients with a BMI of 18.5 to 24, those with BMIs of 40 to 44 and greater than 45 had relative risks of 2.68 and 4.18, respectively (n=6,916). https://www.acpjournals.org/doi/10.7326/m20-3742 268 comments science
- Many people are unable to attend regular healthcare visits because of the pandemic. This is detrimental for those on the osteoporosis drug Denosumab/Prolia. Researcher show that just a short delay of 4-16 weeks can increase risk of spine fracture by 48%, delay over 16 weeks increases risk by 4-fold https://www.acpjournals.org/doi/10.7326/m20-0882 3 comments science
- Speaking does not indicate adequate ventilation or oxygenation - exposing the myth that speaking implies breathing https://www.acpjournals.org/doi/10.7326/m20-4186 505 comments science
- COVID-19 Resurgence Model expects disease activity to resurge rapidly and ICUs to quickly reach capacity when number of contacts between persons returns to >50% of normal, in absence of improved capacity for testing and contact tracing https://www.acpjournals.org/doi/10.7326/m20-2945 90 comments science
- Loss of Smell and Taste in 2013 European Patients With Mild to Moderate COVID-19: "A total of 1754 patients (87%) reported loss of smell, whereas 1136 (56%) reported taste dysfunction." https://www.acpjournals.org/doi/10.7326/m20-2428 4 comments science
- Autopsy Findings and Blood Clots in COVID-19 Patients: Autopsy revealed deep venous thrombosis in 58% of patients in whom venous thromboembolism was not suspected before death. The high incidence of thromboembolic events suggests an important role of COVID-19–induced coagulopathy. https://www.acpjournals.org/doi/10.7326/m20-2003 16 comments science