Hacker News
- Active ingredient in cannabis protects aging brain cells, researchers find https://www.salk.edu/news-release/active-ingredient-in-cannabis-protects-aging-brain-cells/ 14 comments
- The brain’s ability to perceive space expands like the universe https://www.salk.edu/news-release/the-brains-ability-to-perceive-space-expands-like-the-universe/ 4 comments science
- Study shows promise for the development of gene therapies to repair hearing loss by delivering the protein EPS8 via gene therapy, that rescues malfunctioning inner ear hair cells that transduce sound https://www.salk.edu/news-release/discovery-advances-the-potential-of-gene-therapy-to-restore-hearing-loss/ 23 comments science
- Gene therapy rescues malfunctioning inner ear hair cells that transduce sound https://www.salk.edu/news-release/discovery-advances-the-potential-of-gene-therapy-to-restore-hearing-loss/ 286 comments futurology
- Making a memory positive or negative. Researchers pinpoint a neurotransmitter that helps assign positive or negative emotions to a memory. Discovery paves the way for a better understanding of why some people are more likely to retain negative emotions than positive ones (anxiety, depression, PTSD) https://www.salk.edu/news-release/making-a-memory-positive-or-negative/ 25 comments science
- New study found that the best way to explain how the neurons were behaving, was through interaction of microscopic waves of activity rather than interaction of individual neurons. researchers showed how it creates patterns: waves of activity across many neighboring cells, like ocean waves https://www.salk.edu/news-release/an-ocean-in-your-brain-interacting-brain-waves-key-to-how-we-process-information/ 3 comments science
- Scientists surprised to discover flexible decision-making capabilities in a worm with just 302 neurons https://www.salk.edu/news-release/tiny-worms-make-complex-decisions-too/ 9 comments science
- Cellular rejuvenation therapy safely reverses signs of aging in mice. Salk researchers treated mice with anti-aging regimen beginning in middle age and found no increase in cancer or other health problems later on. https://www.salk.edu/news-release/cellular-rejuvenation-therapy-safely-reverses-signs-of-aging-in-mice/ 123 comments science
- In a first for “sonogenetics” researchers control mammalian cells with sound. Researchers pinpoint a sound-sensitive mammalian protein that lets them activate brain, heart, other cells with ultrasound. Method paves the way toward non-invasive versions of brain stimulation, pacemakers, insulin pumps. https://www.salk.edu/news-release/in-a-first-for-sonogenetics-researchers-control-mammalian-cells-with-sound/ 7 comments science
- New route for regulating blood sugar levels independent of insulin. New molecular pathway controls blood glucose, circumventing insulin resistance. https://www.salk.edu/news-release/salk-researchers-find-a-new-route-for-regulating-blood-sugar-levels-independent-of-insulin/ 7 comments science
- SARS-CoV-2 spike proteins alone damage cells https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/ 24 comments science
- How plants sound the alarm about danger. Team led by Salk scientists provides a detailed picture of how plant hormones communicate through gene regulation. https://www.salk.edu/news-release/how-plants-sound-the-alarm-about-danger/ 3 comments science
- Alzheimer’s drug candidates reverse broader aging study shows https://www.salk.edu/news-release/alzheimers-drug-candidates-reverse-broader-aging-study-shows/ 3 comments science
- Researchers report the discovery of three cell types in the eye that detect light and align the brain's circadian rhythm to our ambient light to help the brain tell day from night and establish healthy day-night cycles -- the 1st direct assessment in humans of light responses from these cells. https://www.salk.edu/news-release/three-types-of-cells-help-the-brain-tell-day-from-night/ 16 comments science
- Scientists discover brain circuit in mice that controls compulsive drinking of alcohol. This can potentially have implications for understanding human binge drinking and addiction in the future. https://www.salk.edu/news-release/brain-biomarker-predicts-compulsive-drinking/ 10 comments science
- When neurons are out of shape, antidepressants may not work https://www.salk.edu/news-release/when-neurons-are-out-of-shape-antidepressants-may-not-work/ 14 comments science
- Discovery of a potent neuroprotective chemical in a native California shrub may lead to a treatment for Alzheimer’s disease, tested on mouse nerve cells. Native California tribes, which dubbed the plant “holy herb” in Spanish, have long used Yerba santa for its medicinal properties. https://www.salk.edu/news-release/native-california-medicinal-plant-may-hold-promise-for-treating-alzheimers/ 85 comments science
- Scientists have developed a technique to directly convert cells in an open wound into new skin cells in mice, by reprogramming the cells to a stem-cell-like state, which could be useful for healing skin damage, countering the effects of aging and helping us to better understand skin cancer. https://www.salk.edu/news-release/the-alchemy-of-healing-researchers-turn-open-wounds-into-skin/ 199 comments science
- Eating in 10-hour window can override disease-causing genetic defects, nurture health - Salk scientists discover that periods of fasting can protect against obesity and diabetes, in a new study in mice published in Cell Metabolism. https://www.salk.edu/news-release/eating-in-10-hour-window-can-override-disease-causing-genetic-defects-nurture-health/ 1284 comments science
- Research shows that cells from older people have impaired mitochondria, reducing energy production. The findings could open the door to discovering a clear link between mitochondrial dysfunction and age related neurodegeneration https://www.salk.edu/news-release/impaired-energy-production-may-explain-why-the-brain-is-susceptible-to-age-related-diseases/ 541 comments science
- “Exercise-in-a-pill” boosts athletic endurance by 70 percent in sedentary mice https://www.salk.edu/news-release/exercise-pill-boosts-athletic-endurance-70-percent/ 3 comments science
- Perturbation of the circadian rhythm is a hallmark of cancer and chronic circadian rhythm disruption predisposes individuals to tumour development. Nowresearchers show that drugs that stimulate the circadian cloc are selectively lethal to a wide range of cancer cells. https://www.salk.edu/news-release/salk-scientists-curb-growth-cancer-cells-blocking-access-key-nutrients/ 16 comments science
- Salk scientists curb growth of cancer cells by blocking access to key nutrients through control of circadian clock. https://www.salk.edu/news-release/salk-scientists-curb-growth-cancer-cells-blocking-access-key-nutrients/ 4 comments science
- While most fat cells in the human body store energy, a small subset of brown fat cells does the opposite—burn energy and generate heat. The molecule ERRγ gives this “healthier” brown fat its energy-expending identity, potentially offering a new therapeutic target for diseases related to obesity. https://www.salk.edu/news-release/molecule-gives-energy-burning-brown-fat-identity-lead-drugs-obesity/ 7 comments science
- Exercise pill boosts the endurance of sedimentary mice by 70%. The drug mimics the effects of exercising and causes increased fat burning and stamina. https://www.salk.edu/news-release/exercise-pill-boosts-athletic-endurance-70-percent/ 9 comments science
- New kinds of brain cells revealed http://www.salk.edu/news-release/new-kinds-brain-cells-revealed/ 3 comments science
- Identical twins, not-so-identical stem cells. A new twin study sheds light on what causes reprogrammed stem cells to have different epigenetic patterns. The findings are being used for research and therapeutics, say the researchers. http://www.salk.edu/news-release/identical-twins-not-identical-stem-cells/ 3 comments science
- Juvenile worms behave ambivalently, comparable to human teenagers say researchers http://www.salk.edu/news-release/worms-teenage-ambivalence/ 25 comments science
- Scientists partially reverse aging in mice. http://www.salk.edu/news-release/turning-back-time-salk-scientists-reverse-signs-aging/ 4 comments science
- Molecule slows aging in animals: Researchers have found that an experimental drug candidate aimed at combating Alzheimer’s disease has a host of unexpected anti-aging effects in animals http://www.salk.edu/news/pressrelease_details.php?press_id=2130 23 comments science
- Scientists see motor neurons 'walking' in real time http://www.salk.edu/news/pressrelease_details.php?press_id=2108 4 comments science
- Salk scientists discover how a "mini-brain" in the spinal cord aids in balance http://www.salk.edu/news/pressrelease_details.php?press_id=2070 5 comments science
- Salk researchers have developed an entirely new type of pill - fexaramine - that tricks the body into thinking it has consumed calories, causing it to burn fat. http://www.salk.edu/news/pressrelease_details.php?press_id=2068 10 comments science
- Scientists discover a 'good' fat that fights diabetes http://www.salk.edu/news/pressrelease_details.php?press_id=2055 50 comments science
- Researchers discover off switch for ageing cells http://www.salk.edu/news/pressrelease_details.php?press_id=2052 65 comments science
- Single gene controls jet lag: Researchers discover a master gene responsible for sleep and wake cycles, offering hope for a drug that could help reset sleep http://www.salk.edu/news/pressrelease_details.php?press_id=2046 5 comments science
- Memory relies on astrocytes, the brain's lesser known cells - Salk Institute http://www.salk.edu/news/pressrelease_details.php?press_id=2039 3 comments science
- One injection stops type 2 diabetes in its tracks in mice without side effects. (Not yet tested in humans.) http://www.salk.edu/news/pressrelease_details.php?press_id=2037 4 comments science
- Natural plant compound prevents Alzheimer's disease in mice: Daily dose of the antioxidant fisetin, found in fruits and vegetables, keeps mic (even those with genetic mutations linked to Alzheimer's) from experiencing memory and learning deficits as they age http://www.salk.edu/news/pressrelease_details.php?press_id=655 3 comments science
- Scientists find a surprising degree of variation among genomes of individual neurons from the same brain http://www.salk.edu/news/pressrelease_details.php?press_id=647 4 comments science