Hacker News
- Things I Won’t Work With: Peroxide Peroxides (2014) http://pipeline.corante.com/archives/things_i_wont_work_with/ 27 comments
- A Huntington's Breakthrough? http://pipeline.corante.com/archives/2014/03/28/a_huntingtons_breakthrough.php 12 comments
- Picosecond Protein Watching http://pipeline.corante.com/archives/2012/11/08/picosecond_protein_watching.php 5 comments
- On the 100x Price Rise of a Formerly Generic Drug http://pipeline.corante.com/archives/2011/03/11/makenas_price_what_to_do.php 38 comments
- Expensive Placebos Work Better http://pipeline.corante.com/archives/2015/01/29/expensive_placebos_work_better.php 10 comments science
- If fewer trees increase cardiovascular disease risk based on correlation alone, then Mexican Lemons cause car accidents. http://pipeline.corante.com/archives/2009/04/01/mexican_lemons_to_the_rescue.php 5 comments science
- Things I Won't Work With: Dimethylcadmium http://pipeline.corante.com/archives/2013/05/08/things_i_wont_work_with_dimethylcadmium.php 18 comments science
- Bringing people out of major depression - but for only two hours at a time! A new drug mechanism raises as many questions as it answers. http://pipeline.corante.com/archives/2013/01/18/a_short_rise_out_of_depression.php 5 comments science
- Is obesity partially an infectious disease? A paper on Enterobacter species fulfills Koch's criteria, and suggests new lines of research. http://pipeline.corante.com/archives/2013/01/15/is_obesity_an_infectious_disease.php 6 comments science
- Report: 90% of groundbreaking cancer results from the scientific literature can't be reproduced. Which might help explain why progress has been slow. . . http://pipeline.corante.com/archives/2012/03/29/sloppy_science.php/ 40 comments technology
- Announcing layoffs and a stock buyback on the same day - any CEO that does this should be fired. http://pipeline.corante.com/archives/2012/02/08/buying_back_shares_an_admission_of_defeat.php 2 comments economy
- A Things I Won't Work With post: You can't say it, and you don't want to touch it with a stick. It's hexanitrohexaazaisowurtzitane! http://pipeline.corante.com/archives/2011/11/11/things_i_wont_work_with_hexanitrohexaazaisowurtzitane.php 8 comments technology
- A new form of engineered life (solid work this time). Bacteria forced to use a new DNA base, "way off to the side of all life on Earth". http://pipeline.corante.com/archives/2011/07/06/a_first_step_toward_a_new_form_of_life.php 9 comments science
- Best writeup I've seen so far on Arsenic life. http://pipeline.corante.com/archives/2010/12/02/life_with_arsenic_whod_have_thought.php 131 comments science
- Where do drugs come from? Pharma, Biotech, or Universities, and in what proportions? http://pipeline.corante.com/archives/2010/11/04/where_drugs_come_from_the_numbers.php 3 comments technology
- Do you have to put in 80-hour weeks to do good science? A Johns Hopkins professor goes after his institute's work habits in print, while other scientists loudly disagree. . . http://pipeline.corante.com/archives/2010/09/30/the_hours_you_put_in.php#comments 15 comments science
- Report: scientists are getting older before making their biggest discoveries (and not so many of them work alone any more. . .) http://pipeline.corante.com/archives/2010/05/28/scientific_discovery_getting_older_and_less_lonely.php 6 comments science
- India's Research Culture: "The ancient Sanskrit saying 'baba vakyam pramanam' means 'the words of the elders are the ultimate truth,' thus condemning the type of irreverence inspired by the persistent questioning that is necessary for science" http://pipeline.corante.com/archives/2010/05/26/indias_research_culture.php 3 comments science
- How not to store acetylene http://pipeline.corante.com/archives/2010/05/14/how_not_to_do_it_acetylene_cylinders.php 40 comments science
- Things I Won't Work With: "Godzilla's Gym Socks" - a chemical that leaves anyone who gets near it nauseated for days. . . http://pipeline.corante.com/archives/2010/05/07/things_i_wont_work_with_small_smelly_isocyanides.php 44 comments science
- Homemade morphine? http://pipeline.corante.com/archives/2010/04/28/homemade_morphine.php 6 comments science
- The Alkali Metals Show Their Personalities. http://pipeline.corante.com/archives/2010/03/04/mental_health_break_the_alkali_metals_show_their_personalities.php 4 comments science
- Derek Lowe is a pharmaceutical chemist who has been in the business for over 20 years. Here are the chemicals that he won't work with. http://pipeline.corante.com/archives/things_i_wont_work_with/? 179 comments science
- Reducing your food intake to increase your lifespan? Research suggests that you might keep the carbs, it's the proteins that matter. http://pipeline.corante.com/ 29 comments science
- Scientific journals to ask for political and religious conflict-of-interest statements, as well as financial ones? http://pipeline.corante.com/archives/2009/11/04/are_you_now_or_have_you_ever_been_.php 5 comments science
- Studying the "nocebo effect": patients in clinical trials tend to get the drug's side effects *even when they're not in the group that's taking the drug* http://pipeline.corante.com/archives/2009/10/02/placebos_can_work_the_other_way_too.php 23 comments science
- Real Electrons. Pictures of the S and P orbitals. Not diagrams, actual imaging from real electrons. http://pipeline.corante.com/archives/2009/09/16/real_electrons.php 213 comments science
- Things I Won't Work With: Thioacetone - A stench so powerful that briefly opening a bottle results in immediate nausea in people working in another building hundreds of yards away http://pipeline.corante.com/archives/2009/06/11/things_i_wont_work_with_thioacetone.php 11 comments reddit.com
- Chlorine trifluoride: one of the scarier substances. It's such a strong oxidizer that it will make concrete burn. http://pipeline.corante.com/archives/2008/02/26/sand_wont_save_you_this_time.php 58 comments science
- If you're thinking of welding up a big old tank of liquid nitrogen so it has no pressure release, and then walking away and leaving it. . .you might want to read this first. Just saying. http://pipeline.corante.com/archives/2006/03/08/how_not_to_do_it_liquid_nitrogen_tanks.php??? 22 comments reddit.com
- You'll never guess what the drug industry's done to their R&D spending over the last 30 years. . .especially compared to what they're spending on sales and marketing. http://pipeline.corante.com/archives/2009/07/08/how_much_does_the_drug_industry_spend_on_marketing.php 6 comments reddit.com
- The operator is confronted with the problem of coping with a metal-fluorine fire. For dealing with this situation, I have always recommended a good pair of running shoes. http://pipeline.corante.com/archives/things_i_wont_work_with/ 3 comments reddit.com
- Things I Won't Work With: a compendium of startling chemicals http://pipeline.corante.com/archives/things_i_wont_work_with/ 6 comments science
- "But that's when people start diving out of windows and vomiting into wastebaskets, so the quality of the data start to deteriorate. . ." http://pipeline.corante.com/archives/2009/06/11/things_i_wont_work_with_thioacetone.php 6 comments science
- Ever worked for a place that had its own corporate anthem? "I wanted to clap my hands over my ears, both to shut out the music and to keep my soul from trying to flee my body via my Eustachian tubes. http://pipeline.corante.com/archives/2009/02/25/inspiration_is_where_you_find_it.php 2 comments reddit.com
- Weird stretches of DNA, the only ones that are completely identical in people, rats and mice: What happens when you delete them? http://pipeline.corante.com/archives/2007/11/11/a_real_genetic_headscratcher.php 199 comments reddit.com
- That "Women avoid science careers because they suck" article? Its author doesn't know what he's talking about. http://pipeline.corante.com/archives/2006/03/06/man_hands_on_misery_to_man.php 13 comments reddit.com
- Shit, that fremen stillsuit wouldn't work after all. http://pipeline.corante.com/archives/2005/05/20/outside_reading.php 2 comments reddit.com
- Evolution real time: researches sequence the genome of a bacteria 35 times as they treat a patient with Vancomycin http://pipeline.corante.com/archives/2007/05/22/evolution_in_action.php 66 comments reddit.com
- Scientist begs photographers: "please, no more colored spotlights." http://pipeline.corante.com/archives/2006/07/07/memo_to_the_public_relations_department.php 14 comments reddit.com
Linking pages
- Why Alzheimer's Drugs Keep Failing - Scientific American http://www.scientificamerican.com/article/why-alzheimer-s-drugs-keep-failing/?amp%3Bwt.mc_id=sa_hlth_20140715 6 comments
- Complex molecules made to order in synthesis machine | Nature http://www.nature.com/news/complex-molecules-made-to-order-in-synthesis-machine-1.17113 4 comments
- What does a new drug cost? Part II: The productivity problem | Science-Based Medicine http://www.sciencebasedmedicine.org/index.php/what-does-a-new-drug-cost-part-ii-the-productivity-problem/ 0 comments
- How To Solve It – God of the Machine http://www.godofthemachine.com/?p=596 0 comments
- Molecular modelling's $10-million comeback? | Nature http://www.nature.com/news/2010/100507/full/news.2010.223.html 0 comments