Hacker News
- Beyond headlines of transmitted Alzheimer's, scientists see case for prions https://www.fiercebiotech.com/research/alzheimers-transmission-medical-procedure-builds-case-prion-theory 39 comments
- MDMA approval filing nears after drug hits again in phase 3 https://www.fiercebiotech.com/biotech/mdma-approval-filing-nears-after-drug-hits-again-phase-3-showing-consistent-ptsd 3 comments
- Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85% https://www.fiercebiotech.com/biotech/pfizer-s-oral-covid-19-antiviral-cuts-hospitalization-death-by-85-sending-team-barreling-to 1128 comments
- Know Labs unveils glucose monitor that swaps fingersticks for RF sensors https://www.fiercebiotech.com/medtech/know-labs-unveils-pocket-sized-glucose-monitor-swaps-fingersticks-for-radiofrequency 81 comments
- Excision's CRISPR HIV therapy is heading into human testing after FDA clearance https://www.fiercebiotech.com/biotech/excision-hiv-crispr-gene-editing-therapy-cleared-for-human-studies-by-fda 98 comments
- FDA approves Abbott's Bluetooth-connected pacemaker, defibrillator implants https://www.fiercebiotech.com/medtech/fda-approves-abbott-s-bluetooth-connected-pacemaker-defibrillator-implants 2 comments
- Moderna eyes 'early summer' start for phase 3 Covid-19 vaccine trial https://www.fiercebiotech.com/biotech/moderna-eyes-early-summer-start-for-phase-3-covid-19-vaccine-trial 4 comments
- New Seattle Hub for Synthetic Biology launches to build a ‘genomic smart watch’ https://www.fiercebiotech.com/research/new-seattle-hub-synthetic-biology-launches-build-genomic-smart-watch 2 comments futurology
- Scientists use probiotic bacteria to enhance T cell cancer therapy. The bacteria "tag" the tumors, making them more easily recognizable by the immune system. This could make T cell therapy work for any kind of cancer, not just blood cancer. https://www.fiercebiotech.com/research/probiotics-punch-car-t-therapy-solid-tumors-mice 9 comments science
- UT Austin scientists design safer Cas9 with improved CRISPR gene editing accuracy https://www.fiercebiotech.com/research/ut-austin-scientists-design-safer-cas9-improved-crispr-gene-editing-accuracy 56 comments futurology
- FDA clears AI software for spotting prostate cancer in MRI scans https://www.fiercebiotech.com/medtech/fda-clears-ai-software-spotting-prostate-cancer-mri-scans 3 comments technews
- Aldeyra's dry eye drops make another clinical splash as the company nears NDA submission https://www.fiercebiotech.com/biotech/aldeyras-dry-eye-drops-make-another-clinical-splash-company-nears-nda-submission 3 comments science
- Second Sight's 'bionic eyes' have gone obsolete while still implanted https://www.fiercebiotech.com/medtech/second-sights-bionic-eyes-have-gone-obsolete-while-still-implanted-report-finds 241 comments technews
- Second Sight’s ‘bionic eyes’ have gone obsolete while still implanted, report finds https://www.fiercebiotech.com/medtech/second-sights-bionic-eyes-have-gone-obsolete-while-still-implanted-report-finds 7 comments futurology
- FDA puts LogicBio genome editing therapy trial on hold after 2nd infant suffers adverse event https://www.fiercebiotech.com/biotech/fda-puts-logicbio-genome-editing-therapy-trial-hold-after-second-infant-suffers-adverse 12 comments science
- I'm Long 7252 @ 2.47 should we be worried bout Know Labs? https://www.fiercebiotech.com/medtech/know-labs-unveils-pocket-sized-glucose-monitor-swaps-fingersticks-for-radiofrequency 11 comments senseonics
- BioNTech reports promising data on mRNA cocktail in mouse models of colon cancer and melanoma https://www.fiercebiotech.com/research/biontech-reports-promising-data-mrna-cocktail-mouse-models-colon-cancer-and-melanoma 5 comments science
- BioNTech reports promising data on mRNA cocktail in mouse models of colon cancer and melanoma https://www.fiercebiotech.com/research/biontech-reports-promising-data-mrna-cocktail-mouse-models-colon-cancer-and-melanoma 2 comments futurology
- Rockley Photonics unveils ‘clinic-on-the-wrist’ sensors, offering a potential glimpse at the Apple Watch’s future https://www.fiercebiotech.com/medtech/rockley-photonics-unveils-clinic-wrist-system-offering-a-glimpse-at-apple-watch-s-future 15 comments hardware
- Northwestern U's novel gene-silencing RNA drug shows promise in glioblastoma - Medicine made with real gold nanoparticle cores which can cross the blood-brain barrier to help deliver siRNA to treat brain cancer. https://www.fiercebiotech.com/research/a-novel-gene-silencing-rna-drug-attached-to-a-gold-core-shows-promise-brain-cancer 6 comments science
- Zebrafish reveal regenerative protein that could inspire new treatments for muscle-wasting diseases and aging https://www.fiercebiotech.com/research/zebrafish-reveal-regenerative-protein-could-inspire-new-treatments-for-muscle-wasting 3 comments science
- After setback, Sanofi, GSK take tweaked COVID-19 vaccine into phase 2 https://www.fiercebiotech.com/biotech/after-setback-sanofi-gsk-take-tweaked-covid-19-vaccine-into-phase-2 7 comments europe
- Novavax (NVAX) DD https://www.fiercebiotech.com/biotech/novavax-shares-soar-on-nih-swine-flu-agreement 32 comments wallstreetbets
- Scientists at Hanyang University in Seoul reported that mice lost 20% of their body weight and showed reductions in insulin resistance and inflammation when injected with CRISPR interference that targeted the gene FABP4 which is a significant contributor to obesity. https://www.fiercebiotech.com/research/could-gene-therapy-be-solution-to-obesity-and-diabetes 67 comments science
- Bats can host multiple viruses without ever developing symptoms—even potentially fatal ones like Ebola. The US Army has studied this phenomenon with the hopes of applying it to people. Their study is now published in Cell. https://www.fiercebiotech.com/research/what-bats-are-teaching-us-about-immunity-to-viruses 3 comments science
- Surgery, radiation and chemotherapy just don’t cut it against glioblastoma, with 5-year survival rates as low as 5%. In new research, authors show that CAR-T cells targeting CSPG4 effectively treats glioblastoma in mouse models, with no evidence of antigen loss or tumor escape. https://www.fiercebiotech.com/research/new-target-antigen-could-make-car-t-possible-for-more-glioblastomas 8 comments science
- 9 of 10 individuals who develop lupus are women. Also, XXY individuals have increased incidence of lupus, suggesting that X chromosome dosage could be an important risk factor. Now researchers have found that the gene, TLR7, escapes silencing in lupus and may be a potent drug target for the disease. https://www.fiercebiotech.com/research/targeting-a-toll-like-receptor-could-attack-root-cause-lupus 137 comments science
- A cancer drug may be useful in treating HIV. When doctors treated an HIV-infected lung cancer patient with the immunotherapy drug, Opdivo, they were stunned to discover a huge decrease in the patient’s viral “reservoirs”—hideaways in the body that allow HIV to escape from anti-retroviral treatments. https://www.fiercebiotech.com/research/could-bms-s-immuno-oncology-hit-opdivo-also-attack-hiv 15 comments science
- Researchers have developed a genetically modified version of the herpes virus that infects cancer cells and expresses cytokines that recruit immune cells. When tested in a Phase 2 trial, the virus doubled the response rate when added to standard of care. http://www.fiercebiotech.com/biotech/amgen-s-imlygic-doubles-response-rate-when-added-to-checkpoint-therapy 10 comments science
- Researchers at Duke have created an engineered hybrid of poliovirus and rhinovirus which is capable of selectively killing glioblastoma cells while sparing healthy neurons in mouse and human cell line models. http://www.fiercebiotech.com/research/how-poliovirus-unleashes-attack-glioblastoma 3 comments science
- New anti-aging approach could yield treatments for progeria, other diseases http://www.fiercebiotech.com/research/new-anti-aging-approach-could-yield-treatments-for-progeria-other-diseases 4 comments science
- Mice given ‘exercise in a pill’ show ‘huge increase’ in endurance, say Salk scientists http://www.fiercebiotech.com/research/mice-given-exercise-a-pill-show-huge-increase-endurance-say-salk-scientists 10 comments science
- Platypus venom could give rise to a new class of diabetes treatments http://www.fiercebiotech.com/research/platypus-venom-could-give-rise-to-a-new-class-diabetes-treatments 26 comments science
- Clinton campaign questioned FDA commissioner’s Big Pharma ties: WikiLeaks http://www.fiercebiotech.com/biotech/clinton-campaign-questioned-fda-commissioner-s-big-pharma-ties-wikileaks 27 comments politics
- Sean Parker just got federal backing to run the world’s first-ever CRISPR/Cas9 trial, which could alter the way many diseases, especially cancer, are treated. http://www.fiercebiotech.com/biotech/facebook-napster-billionaire-parker-to-fund-first-ever-crispr-trial 5 comments science
- Nice guy Martin Shkreli bullying teenagers on facebook and being sued by former company RETROPHIN for $59 million. http://www.fiercebiotech.com/story/retrophin-comes-after-shkreli-65m-suit-and-claims-flagrant-mismanagement/2015-08-17 3 comments worldnews
- As CEO of Retrophin, Martin Shkreli bought an old rare-disease drug, Thiola, and raised the price 2000%. Now at, Turing Pharmaceuticals, he's bought old drug and boosted the price 5000%. http://www.fiercebiotech.com/story/why-would-martin-shkreli-hike-old-drug-price-5000-only-moron-would-ask/2015-09-20 10 comments technology
- cancer immunotherapy trials halted: Two deaths in trial of engineered T cells http://www.fiercebiotech.com/story/memorial-sloan-kettering-hits-brakes-engineered-t-cell-cancer-study/2014-04-06 15 comments science
- First successful transplant of retinas made from embryonic stem cells http://www.fiercebiotech.com/story/first-successful-transplant-retinas-made-embryonic-stem-cells/2013-07-22 42 comments science
- Remember the stem cell-based cure for AIDS? Yeah, that experiment was two years old, used unmodified adult stem cells (not embryonic ones), and offers "no hope" for most people with HIV. http://www.fiercebiotech.com/story/first-hiv-cure-comes-very-big-catch/2010-12-15 216 comments science