Hacker News
- Cancer cell lines evolve in ways that affect how they respond to drugs https://www.broadinstitute.org/news/cancer-cell-lines-evolve-ways-affect-how-they-respond-drugs 3 comments
- A biologist, a mathematician, and a computer scientist walk into a foobar http://www.broadinstitute.org/blog/biologist-mathematician-and-computer-scientist-walk-foobar 12 comments
- Open Biology Data https://www.broadinstitute.org/scientific-community/data 4 comments
- Prime editing efficiently corrects cystic fibrosis mutation in human lung cells, finds a new study - The genome editing approach targets the most common genetic cause of the disease and could enable a one-time treatment as effective as existing daily therapies. https://www.broadinstitute.org/news/prime-editing-efficiently-corrects-cystic-fibrosis-mutation-human-lung-cells 3 comments science
- Prime editing efficiently corrects cystic fibrosis mutation in human lung cells https://www.broadinstitute.org/news/prime-editing-efficiently-corrects-cystic-fibrosis-mutation-human-lung-cells 12 comments technology
- Scientists work out the effects of exercise at the cellular level: Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions https://www.broadinstitute.org/news/scientists-work-out-effects-exercise-cellular-level 6 comments science
- Scientists have identified specific species of bacteria that consume cholesterol in the gut and may help lower cholesterol and heart disease risk in people. Findings lay the groundwork for more targeted investigations of how changes to the microbiome affect health and disease. https://www.broadinstitute.org/news/scientists-link-certain-gut-bacteria-lower-heart-disease-risk 14 comments science
- Schizophrenia and aging may share a common biological basis. Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues. https://www.broadinstitute.org/news/schizophrenia-and-aging-may-share-common-biological-basis 12 comments science
- How chromosome imbalances can drive cancer https://www.broadinstitute.org/news/how-chromosome-imbalances-can-drive-cancer 2 comments science
- New image-based cellular profiling tool peers deeply into metabolic biology https://www.broadinstitute.org/news/lipocyte-profiler-metabolic-biology-tool 2 comments science
- Scientists reveal cellular changes unique to early Alzheimer’s disease. https://www.broadinstitute.org/news/scientists-reveal-cellular-changes-unique-early-alzheimers-disease 9 comments science
- New technique improves detection of cancer DNA in blood, MIT study shows https://www.broadinstitute.org/news/new-technique-improves-detection-cancer-dna-blood 3 comments science
- New programmable gene editing proteins found outside of CRISPR systems. The discovery provides evidence that natural RNA-guided enzymes are among the most abundant proteins on earth, pointing toward a vast new area of biology that is poised to drive the next revolution in genome editing technology. https://www.broadinstitute.org/news/new-programmable-gene-editing-proteins-found-outside-crispr-systems 13 comments futurology
- A strip of paper can now indicate presence of pathogens, tumor DNA or any genetic signature of interest. 100-fold greater sensitivity, the ability to detect multiple targets at once, and other new features further enhance SHERLOCK's power for detecting genetic signatures- Broad institute, Harvard https://www.broadinstitute.org/news/sherlock-team-advances-its-crispr-based-diagnostic-tool 5 comments science
- Science AMA Series: Dr. Anne Carpenter, Institute Scientist at the Broad Institute of MIT and Harvard providing background on the 2018 Data Science Bowl and questions on cell biology, microscopy, and computational biology. Ask Me Anything. http://broadinstitute.org/~anne/ 48 comments science
- Antibiotics alter the infectious microenvironment and may reduce the ability of immune cells to kill bacteria https://www.broadinstitute.org/news/antibiotics-alter-infectious-microenvironment-and-may-reduce-ability-immune-cells-kill-bacteria?utm_source=twitter&utm_content=news-story%252ccollins%252cantibiotic-resistance&utm_medium=social&utm_campaign=broad+institute 3 comments science
- Unraveling tangled transcriptional webs reveals a dysfunction program in T cells https://www.broadinstitute.org/news/8617 8 comments science
- A new study in infant gut microbiome supports the hygiene hypothesis: infants in the western countries have limited exposure to various microorganisms which has implications in the development of their immune system. This makes them prone to autoimmune diseases (e.g. type 1 diabetes) and allergies. https://www.broadinstitute.org/news/8131 531 comments science
- Scientists use bioinformatics to report the discovery of 3 additional CRISPR enzymes to bolster the growing list of nucleases for precision genetic engineering http://www.broadinstitute.org/news/7360?utm_medium=twitter&utm_source=twitterfeed 5 comments science
- Scientists have discovered a new genome editing system which may offer even more precision and flexibility for editing than CRISPR https://www.broadinstitute.org/news/7272 3 comments science
- Researchers find link between microbiome and type 1 diabetes: microbiome species diversity changes prior to onset of the disease, most notably with enrichment of species associated with inflammation http://www.broadinstitute.org/news/6451 5 comments science
- r/science is currently making a lot of noise about a newly released data-exploration tool called MINE. What do you guys think? http://www.broadinstitute.org/news/3784 12 comments statistics
- Scientists create new algorithm to automatically detect and quantify any relationship in a dataset http://www.broadinstitute.org/news/3784 252 comments science