- Walking pace and handgrip strength can indicate dementia risk. Education, physical activity, and comorbidities typically associated with a higher risk of cardiovascular diseases, such as high blood pressure and diabetes, all failed to modify these associations. https://alzres.biomedcentral.com/articles/10.1186/s13195-022-01158-6 4 comments science
- Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer’s dementia (Oct 2022) https://alzres.biomedcentral.com/articles/10.1186/s13195-022-01084-7 2 comments science
- Glucose metabolism and AD: evidence for a potential diabetes type 3 https://alzres.biomedcentral.com/articles/10.1186/s13195-022-00996-8 3 comments science
- [deleted by user] https://alzres.biomedcentral.com/articles/10.1186/s13195-021-00783-x 2 comments science
- GPS driving: a digital biomarker for preclinical Alzheimer disease. Researchers developed a machine learning model based on analyzing driving behavior derived from GPS data loggers to identify preclinical Alzheimer's Disease in place of more complicated diagnostics https://alzres.biomedcentral.com/articles/10.1186/s13195-021-00852-1#Sec2 8 comments science
- Data on data on 247,149 people has found people with mild cognitive impairment (MCI) who engage in as little as 10 minutes of moderate to vigorous exercise a few times a week may be helping to slow the progression to Alzheimer’s or similar dementia https://alzres.biomedcentral.com/articles/10.1186/s13195-020-00707-1 4 comments science
- A new vaccine effectively reduced beta-amyloid (Aβ) and tau pathology in bigenic mice, by generating high Aβ- and tau-specific antibodies that led to significant reductions of both pathologies in the brain, supporting further development of this vaccine for testing in human Alzheimer’s disease. https://alzres.biomedcentral.com/articles/10.1186/s13195-019-0556-2 12 comments science