- Reduced mitochondria have an essential function for the organism, which is not the synthesis of iron-sulfur cofactors, but the synthesis of methylated compounds for the cytosol. https://www.cell.com/current-biology/fulltext/S0960-9822(22)01673-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982222016736%3Fshowall%3Dtrue#secsectitle0075 2 comments science