- In 2014 Andrew Luck led the Colts to the second biggest comeback in the history of the NFL when they overcame a 28 point deficit to defeat the Chiefs. The only bigger comeback happened in 1993 when current Colts head coach Frank Reich overcame a 32 point defect to defeat the Houston Oilers https://en.m.wikipedia.org/wiki/the_comeback_(american_football) 19 comments nfl