Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis | Brain

Researchers identified brain circuits that, when injured, underlie hidden consciousness, or cognitive motor dissociation (CMD), where patients are unable to respond to commands, making them appear unconscious despite having awareness. This occurs in about 15% to 25% of patients with brain injuries. https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awad197/7236061 3 comments 15/8/2023 science

Properties of REM sleep alterations with epilepsy https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac499/7056579#.ZA1U5PzVT88.reddit 2 comments 12/3/2023 science

Acid glia in REM sleep https://doi.org/10.1093/brain/awac499 2 comments 4/3/2023 science

Tilavonemab in early Alzheimer’s disease: results from a phase 2, randomized, double-blind study https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awad024/7024804?u= 22 comments 6/2/2023 science

Cerebrovascular insulin receptors are defective in Alzheimer’s disease https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac309/6761474?login=false 73 comments 18/12/2022 science

Local brain environment changes associated with epileptogenesis https://doi.org/10.1093/brain/awac355 4 comments 26/11/2022 science

New research reveals why pain feels worse at night https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac147/6637506?guestAccessKey=e94c8f79-7fca-42ca-98e2-085eb26400c3&login=false 4 comments 11/9/2022 science

Colorblindness in children could be cured completely, shows groundbreaking study | Two of the four participants showed partial recovery using gene therapy. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac226/6673168?login=false 47 comments 25/8/2022 science

Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac224/6659752?login=false 2 comments 12/8/2022 science

Head Injuries in Children Linked to Reduced Brain Size and Learning Difficulties https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac130/6618291 17 comments 11/7/2022 science

Brains can be hotter than the rest of our bodies, especially in women: Healthy human brains can sometimes register temperatures of 40.9 °C – a couple of degrees higher than the rest of the body – with the highest temperatures associated with the second half of the menstrual cycle. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awab466/6604351?login=false 43 comments 26/6/2022 science

The temperature of the healthy human brain varies much more than previously believed.In healthy men and women, where oral temperature is typically less than 37°C, average brain temperature is 38.5°C, with deeper brain regions often exceeding 40°C, particularly in women during the daytime. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awab466/6604351 145 comments 14/6/2022 science

Researchers identify rise in Guillain-Barré syndrome following AstraZeneca vaccine: Overall, following a first dose of AstraZeneca vaccine there were 5.8 excess GBS cases per million doses of vaccine. First doses of Pfizer and Moderna and second doses of any vaccination showed no excess GBS risk. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac067/6532037?login=false 18 comments 31/5/2022 science

human cognition-enhancing CORD7 mutation increases active zone number and synaptic release | Brain https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awac011/6505110 14 comments 13/5/2022 science

Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma | Brain https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab320/6459638?login=false 2 comments 8/3/2022 science

Cancer diagnosis is associated with a lower burden of dementia and less Alzheimer’s-type neuropathology | Brain https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awac035/6517521 2 comments 3/2/2022 science

Acute and chronic neurological disorders in COVID-19: potential mechanisms of disease https://doi.org/10.1093/brain/awab302 13 comments 7/1/2022 science

ADHD drug atomoxetine may help to slow the progression of Alzheimer’s disease. Norepinephrine is thought to reduce inflammation and to encourage trash-removing cells called microglia to clear out aggregates of proteins such as beta-amyloid and Tau. https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab452/6469022?redirectedFrom=fulltext 43 comments 1/1/2022 science

Volitional control of individual neurons in the human brain https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab370/6384572 6 comments 11/10/2021 science

impact of smoking cessation on multiple sclerosis disease progression https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awab385/6384574 2 comments 11/10/2021 science

Neuroscientists have found no significant association between COVID-19 and the potentially paralysing and sometimes fatal neurological condition Guillain-Barré syndrome. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaa433/6031905 5 comments 14/12/2020 science

Parkinson’s disease comprises two subtypes, suggests new study. A brain-first (top-down) type, where pathology arises in the brain; and a body-first (bottom-up) type that originates in the intestine or peripheral nervous system and then spreads to the brain. https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awaa238/5896254 4 comments 28/9/2020 science

SARS-CoV-2 generally attacks the lungs, but are also stressing its effects on the brain in a fraction of patients: Neurologists in the UK noted an uptick this spring in cases of a potentially fatal condition called acute disseminated encephalomyelitis (ADEM). https://academic.oup.com/brain/article/doi/10.1093/brain/awaa240/5868408 199 comments 13/7/2020 science

Studies find that MRI-guided high intensity focused ultrasound--which is a novel, non-invasive, image-guided procedure that is able to remove brain tissue with submillimetre precision-- is able to treat troublesome tremors in Parkinson's Disease, by targetting multiple specific brain centres. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaa107/5856628#.xu_t4vebv_k.twitter 12 comments 21/6/2020 science

In Alzheimer’s disease, tau, an abnormal protein, spreads in a prion-like manner from neuron to neuron within the brain, similar to the spread of an infection, to cause nerve cell death, finds a new study using advance brain imaging. Blocking its spread may prevent the disease from taking hold. https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awx347/4775021 781 comments 9/1/2018 science

Lesion model of envy and Schadenfreude: legal, deservingness and moral dimensions as revealed by neurodegeneration https://academic.oup.com/brain/article/doi/10.1093/brain/awx269/4588353 6 comments 3/11/2017 cogsci

People who hear voices that other people can't hear may use unusual skills when their brains process new sounds, according to research. https://academic.oup.com/brain/article/doi/10.1093/brain/awx206/4085330/distinct-processing-of-ambiguous-speech-in-people 34 comments 21/8/2017 science

The use of functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) may be able to identify ICU patients with severe traumatic brain injuries who have a level of consciousness not revealed by the standard bedside neurological examination, in order to make end-of-life decisions. https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awx176 5 comments 23/7/2017 science

Trazodone among drugs found to prevent neurodegeneration in mice : suggests new approach for slowing progression of neurodegenerative disease https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awx074 39 comments 20/4/2017 science

Link found between concussions, Alzheimer's disease https://academic.oup.com/brain/article-abstract/doi/10.1093/brain/aww344/2888535/mild-traumatic-brain-injury-is-associated-with?redirectedfrom=fulltext 4 comments 16/1/2017 science

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