- The overdose mortality rate among U.S. adolescents 14 to 18 years old rose by 94% between 2019 and 2020, from 2.36 deaths per 100,000 population to 4.57 per 100,000. Synthetic drugs like fentanyl as driving a spike in overdose deaths among teens. https://jamanetwork.com/journals/jama/fullarticle/2790949?guestAccessKey=0ad128b6-7d7c-4319-bbeb-51e13d9c4f12 35 comments science