- Effective treatments for depression include more than 20 commonly prescribed antidepressants (particularly amitriptyline) and 6 psychological therapies (especially behavioral activation), according to a recent JAMA review of randomized clinical trials. https://www.psychologytoday.com/intl/blog/finding-a-new-home/202407/the-latest-on-the-medications-and-therapies-that-treat-depression 13 comments science