- LSD microdosing does not appear to improve mood or cognitive ability, according to new placebo-controlled study https://www.psypost.org/2022/06/lsd-microdosing-does-not-appear-to-improve-mood-or-cognitive-ability-according-to-new-placebo-controlled-study-63277 900 comments science
- Final Results of a Randomized, Placebo-Controlled, Two-Arm, Parallel Clinical Trial of Proxalutamide for Hospitalized COVID-19 Patients: A Multiregional, Joint Analysis of the Proxa-Rescue AndroCoV Trial https://www.cureus.com/articles/80171-final-results-of-a-randomized-placebo-controlled-two-arm-parallel-clinical-trial-of-proxalutamide-for-hospitalized-covid-19-patients-a-multiregional-joint-analysis-of-the-proxa-rescue-androcov-trial#article-community-discussion 5 comments science
- The adjunctive use of CBD is associated with a reduction in patients’ use of antipsychotic medicines, according to placebo-controlled trial data published in the journal Frontiers in Psychiatry. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599279/ 3 comments science
- MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study ($MNMD) https://www.nature.com/articles/s41591-021-01336-3 62 comments wallstreetbets
- Low doses of LSD (5 - 10 micrograms) demonstrated selective, beneficial effects on mood and cognition in a placebo-controlled, crossover trial (N=24) https://www.sciencedirect.com/science/article/pii/s0924977x20309111?dgcid=rss_sd_all 265 comments science
- Coronil: "Randomised placebo-controlled clinical trials conducted, have relayed the details to the ministry of AYUSH https://www.hindustantimes.com/india-news/patanjali-launches-covid-19-drugs-centre-seeks-details-here-s-what-the-company-said/story-gpcrpcukj4vbufsidq53ep.html 4 comments india
- Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial https://www.thelancet.com/journals/lancet/article/piis0140-6736(20)30934-x/fulltext 3 comments science
- Antidepressant SNRI medications reduce connectivity in the brain’s pain network, finds a new MRI brain scan (double-blind, placebo-controlled) study, which suggests that for some depressed people, the pain network may play an important role, even if they are not describing symptoms of physical pain. https://www.psypost.org/2019/07/antidepressant-snri-medications-reduce-connectivity-in-the-brains-pain-network-54093 8 comments science
- Hormone treatment may improve social behavior in people with autism, suggests a new randomized placebo-controlled pilot trial, that found that intranasal vasopressin improves social deficits in children with autism. https://www.upi.com/health_news/2019/05/02/hormone-treatment-may-improve-social-behavior-in-people-with-autism/8521556833409/ 3 comments science
- Illicit use of ADHD meds won't boost grades: Drugs like Adderall do not improve, and can actually impair, brain function in healthy students who take the drug hoping for an intelligence boost, finds a new double-blind, placebo-controlled pilot study. https://www.upi.com/health_news/2018/07/26/illicit-use-of-adhd-meds-wont-boost-grades-study/8381532657874/ 3 comments science
- An innovative new drug, Evolocumab, can prevent heart attacks and strokes by cutting bad cholesterol to unprecedented levels on a background of statin therapy, in a large randomized, double-blind, placebo-controlled trial involving 27,564 patients published in the NEJM. http://www.nejm.org/doi/full/10.1056/nejmoa1615664 33 comments science
- Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799017https:/jamanetwork.com/journals/jamanetworkopen/fullarticle/2799017 4 comments science
- Placebo response reveals unconscious bias among white patients toward female, Black physicians https://www.statnews.com/2022/06/28/placebo-response-bias-against-female-black-physicians/ 128 comments science
- Much research shows therapy can be less helpful or even detrimental to some clients, while money, self-help, placebos, and medication can be more helpful in solving well-being and quality of life problems. Psychotherapy, on the whole, doesn't appear to meet the goals it sets. https://cognitiontoday.com/is-therapy-worth-it-side-effects-of-therapy-and-how-to-heal-on-your-own/ 9 comments philosophy
- Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2784694 6 comments science
- Mild zaps to the brain can boost a pain-relieving placebo effect. The finding raises the possibility of enhancing the power of expectations to improve treatments. https://www.sciencenews.org/article/brain-mild-zaps-boost-placebo-effect-pain-relief-neuroscience 3 comments science
- In adults with severe COVID-19, remdesivir compared with placebo probably improves recovery by a large amount (absolute risk difference [ARD] range, 7% to 10%) and may result in a small reduction in mortality (ARD range, -4% to 1%) and a shorter time to recovery or clinical improvement. https://www.acpjournals.org/doi/10.7326/m20-5752 9 comments science
- Large review of studies comparing placebo treatment to no treatment finds little evidence of "placebo effect" for objective outcomes compared to no treatment https://www.nejm.org/doi/full/10.1056/nejm200105243442106 23 comments science
- A single dose of acetaminophen may make users more willing to take risks, a new study (n=545) found. Compared to those who took a placebo, acetaminophen users took more risks in a game where they could win/lose rewards. They also rated activities like bungee jumping as less risky. https://news.osu.edu/a-pain-reliever-that-alters-perceptions-of-risk/ 196 comments science
- Nevada governor condemns Las Vegas mayor's push to reopen city, says he won't allow Nevadans to be "placebo" https://www.newsweek.com/nevada-governor-condemns-las-vegas-mayors-push-reopen-city-says-he-wont-allow-nevadans-1499651 10 comments politics
- Supplementation with n−3 fatty acids did not result in a lower incidence of major cardiovascular events or cancer than placebo. https://www.nejm.org/doi/full/10.1056/nejmoa1811403 15 comments science
- Expensive Shams Are the Way to Go, Apparently: The nocebo effect mirrors the placebo effect, complicating drug trials. http://blogs.sciencemag.org/pipeline/archives/2017/10/06/expensive-shams-are-the-way-to-go-apparently 10 comments science
- How much does the placebo effect influence human health? https://www.reddit.com/r/askscience/comments/6l3s62/how_much_does_the_placebo_effect_influence_human/ 5 comments askscience
- When love hurts, a placebo can help http://www.colorado.edu/today/2017/04/24/when-love-hurts-placebo-can-help 3 comments science
- America’s Placebo President? http://www.the-american-interest.com/2017/03/06/americas-placebo-president/ 5 comments politics
- The placebo effect was specifically studied as an intervention in a randomized controlled trial, and it was found to improve outcomes 6 months after heart surgery and to lower inflammatory markers, suggesting it may be useful as a short-term intervention even in highly invasive medical procedures. http://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-016-0767-3 62 comments science
- Study Finds Knowingly Taking Placebo Pills Eases Pain http://www.bidmc.org/news/prlandingpage/2016/october/kaptchuk-placebo-effect.aspx 11 comments science
- Depressed patients who respond to placebo drugs get the most help from real ones http://www.psypost.org/2015/09/placebo-power-depressed-people-who-respond-to-fake-drugs-get-the-most-help-from-real-ones-38044 3 comments science
- New uk cancer trial so effective, placebo group given medication based on ethical grounds. How accurate is this? http://www.telegraph.co.uk/science/science-news/10893387/cancer-pill-fights-disease-and-gives-lifelong-protection.html 23 comments science
- British scientists discover drug that fight all kinds of cancer and offers lifelong protection. On a trial of leukaemia patients, it worked so well the control group taking placebos was immediately switched to the drug on ethical grounds http://www.telegraph.co.uk/science/science-news/10893387/cancer-pill-fights-disease-and-gives-lifelong-protection.html 4 comments worldnews
- Placebo effect largely ignored in psychological intervention studies http://www.eurekalert.org/pub_releases/2013-07/uoia-pel070813.php#.udv7iknic2g.reddit 3 comments science
- Acupuncture Is Theatrical Placebo http://www.sciencebasedmedicine.org/acupuncture-doesnt-work/ 3 comments science
- U.K. doctors admit doling out ‘useless drugs’ for placebo effect | Health | Life http://life.nationalpost.com/2013/03/21/pill-pushers-u-k-doctors-admit-regularly-doling-out-useless-drugs-to-induce-placebo-effect/ 6 comments worldnews
- People can't even take a placebo without fucking up. http://www.youtube.com/watch?amp%3Bfeature=player_embedded&v=O1Q3jZw4FGs 92 comments science
- Placebo may work even if patients know it is a placebo. Findings suggest that rather than mere positive thinking, there may be significant benefit to the very performance of medical ritual. http://www.guardian.co.uk/science/2010/dec/22/placebo-effect-patients-sham-drug 19 comments science
- No Standard for the Placebo http://www.sciencedaily.com/releases/2010/10/101018174335.htm 20 comments science
- Homeopathic remedies = Sugar pills = placebos, they should no longer be paid for by the UK National Health Service http://www.newscientist.com/article/dn18559-stop-funding-homeopathy-say-british-mps.html 7 comments science
- A clear and comprehensible explanation of the placebo effect http://scienceblogs.com/pharyngula/2010/02/ben_goldacre_on_the_placebo_ef.php 17 comments science
- The placebo effect has an evil twin – the nocebo effect – which can make you think yourself ill, or even dead! http://www.newscientist.com/article/mg20227081.100-the-science-of-voodoo-when-mind-attacks-body.html 3 comments science
- Alzheimer's breakthrough: “The people on placebo lost an average of 7 percent of their brain function over six months whereas those on treatment didn’t decline at all,” http://www.msnbc.msn.com/id/25918231/ 117 comments science