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- Why don't we know how antidepressants work yet? https://www.chemistryworld.com/features/why-dont-we-know-how-antidepressants-work-yet/4019673.article 112 comments
- Antidepressants Work Better Than Sugar Pills Only 15 Percent of the Time (2022) https://www.newsweek.com/2022/09/30/antidepressants-work-better-sugar-pills-only-15-percent-time-1744656.html 33 comments
- Antidepressants may not work http://money.cnn.com/2008/01/16/news/companies/antidepressants/ 20 comments reddit.com
- Antidepressants work, but just not how scientists thought they worked https://theconversation.com/antidepressants-work-but-just-not-how-scientists-thought-they-worked-123792 65 comments science
- How depression and antidepressant drugs work http://sciencebulletin.org/archives/1359.html 3 comments science
- When neurons are out of shape, antidepressants may not work https://www.salk.edu/news-release/when-neurons-are-out-of-shape-antidepressants-may-not-work/ 14 comments science
- Study finds antidepressant drugs don't work http://www.independent.co.uk/life-style/health-and-wellbeing/health-news/antidepressant-drugs-udontu-work-ndash-official-study-787264.html 4 comments science
- UK teachers resorting to antidepressants and alcohol to cope with work https://www.independent.co.uk/news/uk/home-news/uk-teachers-work-pressure-survey-b2521162.html 24 comments europe
- New Research Shows Why Antidepressants May Not Work https://memod.com/ScienceSimplified/why-antidepressants-may-not-work-5014 8 comments science
- The drugs do work: antidepressants are effective, study shows https://www.theguardian.com/science/2018/feb/21/the-drugs-do-work-antidepressants-are-effective-study-shows?cmp=share_iosapp_other 44 comments science
- Antidepressants work for treating depression, study finds https://www.irishtimes.com/news/health/antidepressants-work-for-treating-depression-study-finds-1.3401570 29 comments nottheonion
- The drugs do work: antidepressants are effective, study shows https://www.theguardian.com/science/2018/feb/21/the-drugs-do-work-antidepressants-are-effective-study-shows?cmp=share_androidapp_reddit_is_fun 12 comments science
- Excercise works just as well as antidepressants, according to new study http://www.brandweeknrx.com/2007/11/excercise-works.html 18 comments science
- Why do antidepressants take weeks to work? New study reveals https://interestingengineering.com/health/why-do-antidepressants-take-weeks-to-work-new-study-reveals 13 comments health
- Antidepressants work better than sugar pills only 15 percent of the time https://www.newsweek.com/2022/09/30/antidepressants-work-better-sugar-pills-only-15-percent-time-1744656.html 24 comments science
- Peter Molyneux: Working for Microsoft Is Like Taking Antidepressants http://wind8apps.com/peter-molyneux-microsoft-antidepressants/ 3 comments business
- Artificial intelligence helps predict whether antidepressants will work in patients https://www.amsterdamumc.org/en/spotlight/artificial-intelligence-helps-predict-whether-antidepressants-will-work-in-patients.htm 5 comments technology
- New theoretical work explains why the most commonly used antidepressant may initially not work http://www.sciencedirect.com/science/article/pii/s136466131400237x 3 comments science
- TIL that the commonly used antidepressant "Wellbutrin" never actually worked. And has been known not work for around 4 years. http://www.forbes.com/sites/davidmaris/2012/10/10/fda-recall-points-to-serious-problems-at-the-fda/ 28 comments worldnews
- One of the largest studies of modern antidepressant drugs has found that they don't work http://www.belfasttelegraph.co.uk/health/article3466137.ece 153 comments reddit.com
- New evidence has emerged showing ketamine's mechanism of rapid antidepressant effect. The findings indicated ketamine works by increasing the concentration of β-endorphin and activation of opioid receptors in the medial prefrontal cortex. https://www.nature.com/articles/s41398-024-02796-0 67 comments science
- Artificial intelligence helps predict whether antidepressants will work in patients. By inputting a brain scan and an individual's clinical information into an AI algorithm, researchers from Amsterdam UMC and Radboudumc could see up to 8 weeks faster whether or not the medication would work https://www.amsterdamumc.org/en/spotlight/artificial-intelligence-helps-predict-whether-antidepressants-will-work-in-patients.htm 93 comments science
- Commuters who cycle to work are less likely to be prescribed antidepressants. Analysis of almost 380,000 people living in Scotland suggests commuting by bike reduces the risk of ill mental health. https://academic.oup.com/ije/advance-article/doi/10.1093/ije/dyad153/7529101?searchresult=1 125 comments science
- Thousands taking antidepressants for pain despite insufficient evidence they work, say experts | Science & Tech News https://news.sky.com/story/amp/thousands-taking-antidepressants-for-pain-despite-insufficient-evidence-they-work-say-experts-12877406 112 comments science
- Widely used antidepressants cause “emotional blunting”, according to research that offers new insights into how the drugs may work and their possible side-effects. Volunteers less responsive to positive and negative feedback after course of serotonin-controlling drugs https://www.cam.ac.uk/research/news/scientists-explain-emotional-blunting-caused-by-common-antidepressants 705 comments science
- REVEALED: Big Pharma Lying About Antidepressants (AD) For Decades. AD work better than sugar pills for only 15% of the patients. Yet 43 million Americans were on AD before the pandemic. https://youtu.be/q4laCxbYgRg 2 comments economy
- A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor - Work sets the stage for the discovery of new kinds of antidepressants, anti-anxiety drugs, and treatments for substance use disorders http://news.unchealthcare.org/news/2020/september/a-scientific-first-how-psychedelics-bind-to-key-brain-cell-receptor 7 comments science
- Male birds sing less to females on antidepressants. The researchers studied the birds at sewage works where they flock to feed all year round. The worms, maggots and flies at sewage treatment plants have been found to contain many different pharmaceuticals, including Prozac. https://www.york.ac.uk/news-and-events/news/2018/research/male-birds-sing-less-to-females-on-antidepressants/ 13 comments science
- Antidepressants might fail if you use your phone in bed, study suggests - Antidepressants might work by increasing users' sensitivity to light, an Australian study suggests. But, conversely, artificial light at night – such as blue light from a phone screen – might stop the medication working. https://www.theage.com.au/national/antidepressants-might-fail-if-you-use-your-phone-in-bed-study-suggests-20180924-p505nz.html 22 comments science
- Antidepressants might fail if you use your phone in bed, study suggests - Antidepressants might work by increasing users' sensitivity to light, an Australian study suggests. But, conversely, artificial light at night – such as blue light from a phone screen – might stop the medication working. https://www.theage.com.au/national/antidepressants-might-fail-if-you-use-your-phone-in-bed-study-suggests-20180924-p505nz.html 4 comments worldnews
- Strong activity in a specific section of the brain can help predict the success of antidepressant drugs, a study has found. The work could make it easier to choose the right therapy for people with serious depression, and possibly even improve our understanding of the causes of the condition. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2678040 3 comments science
- Men working in human services occupations like social work, healthcare, childcare and teaching are up to twice as likely as those in any other occupation to use antidepressants, a major European study has found http://oem.bmj.com/content/early/2018/01/25/oemed-2017-104803 49 comments science
- One in ten UK teachers taking antidepressants to cope with work stresses - Union leaders have called for 'mental health first-aid' to be made available in all schools, allowing both staff and pupils access to professional counselling http://www.independent.co.uk/news/education/education-news/teachers-antidepressants-stress-workload-suicidal-one-in-ten-nasuwt-a7684466.html 12 comments worldnews
- Researchers at the University of Illinois at Chicago have discovered one reason antidepressants drugs take so long to work, and their finding could help scientists develop faster-acting drugs in the future. http://www.psypost.org/2016/07/antidepressants-take-long-work-44061 10 comments science
- Antidepressants found at home of Germanwings co-pilot Andreas Lubitz - Germanwings Pilot had been previously declared unfit to work by doctors. http://edition.cnn.com/2015/03/29/europe/france-germanwings-plane-crash-main/index.html 95 comments worldnews
- Antidepressants show potential for postoperative pain: Researchers reviewed 15 trials to determine whether the use of antidepressants for pain relief post-surgery would work more effectively than painkillers such as opioids, local anesthetics, or acetaminophen https://www.queensu.ca/news/articles/antidepressants-show-potential-postoperative-pain 9 comments science
- Antidepressant lithium accumulates more strongly in white matter of the brain than in grey matter; thus, it may work differently from synthetic psychotropic drugs. Also, studies have shown that a higher natural lithium content in drinking water leads to a lower suicide rate in the general population http://www.tum.de/en/about-tum/news/press-releases/short/article/31053/ 46 comments science
- Scientists have uncovered a new chemical process that may explain how antidepressants like Prozac work. The newly found mechanism also suggests why the drugs take weeks to start helping and may one day point to new therapies for depression. http://www.sciencenews.org/view/generic/id/63457/title/minimolecule_may_explain_how_antidepressants_work 13 comments science
- "Drug therapy works on the assumption that depression is a disease, and that like an infection can clear with antibiotics, depression can clear with antidepressants." http://www.theage.com.au/news/opinion/healing-the-mind-is-about-more-than-medicine/2008/03/02/1204402269517.html 10 comments reddit.com
- BOSTON (Reuters) - Nearly a third of antidepressant drug studies are never published in the medical literature and nearly all happen to show that the drug being tested did not work http://www.reuters.com/article/topnews/idusn1663594120080117?feedtype=rss&feedname=topnews&rpc=22&sp=true 6 comments reddit.com