- British to sequence 100,000 genomes. http://www.reuters.com/article/2012/12/10/us-britain-dna-database-idusbre8b900320121210 17 comments science
- Large genome deletions (up to 100 kb) possible by Type I CRISPR/Cas https://www.sciencedirect.com/science/article/abs/pii/s1097276519302175 4 comments science
- Can you do 100 edits on a single (human) genome with CRISPR, or is the number limited ? https://www.reddit.com/r/askscience/comments/69op5w/can_you_do_100_edits_on_a_single_human_genome/ 14 comments askscience
- Canadians Launch Genome Sequencing Project and Hope to Get 100,000 Volunteer Donors. http://www.theglobeandmail.com/news/national/time-to-lead/would-you-make-your-dna-and-health-data-public-if-it-may-help-cure-disease/article6090038/?page=1 5 comments science
- Ultima Genomics Claims the $100 Genome and Raises $600M to Go Even Lower https://singularityhub.com/2022/06/05/ultima-genomics-claims-the-100-genome-and-raises-600m-to-go-even-lower/ 20 comments futurology
- TR10:"...entire human genome can be read in eight hours for $100 or less....in five years." https://www.technologyreview.com/read_article.aspx?ch=specialsections&sc=tr10&id=22112 10 comments technology
- An unprecedented view of gene regulation. MIT engineers’ new technique analyzes the 3D organization of the genome at a resolution 100 times higher than before. https://news.mit.edu/2023/unprecedented-view-3d-genome-0508 2 comments science
- 100 million lab animals die every year -- New research from Sweden could help alleviate much of this with genome-wide profiling http://www.thinkonthat.com/archives/2706 4 comments science
- "[Humans are] 90 percent microbial and 10 percent human. There's also an estimated 100 times more microbial genes than the genes in our human genome." http://www.npr.org/templates/story/story.php?storyid=129862107 270 comments science
- Why Bionano Genomics Stock Skyrocketed More Than 100% Today | The genetic testing specialist's tools could help to improve care for people with autism. https://www.fool.com/investing/2021/01/04/why-bionano-genomics-stock-skyrocketed-more-than-1/ 102 comments wallstreetbets
- Scientists retreive RNA from 100-year-old lung specimen from Berlin museum—and suggest measles arose 1500 years earlier than previously thought. Only three genomes from measles viruses occuring before 1990 are known. https://science.sciencemag.org/content/366/6472/1517 3 comments science
- UK National Health Service to offer paid-for genetic blueprints that predict health risks - The 100,000 Genomes Project produced thousands of genetic blueprints sequenced from NHS patients with cancer and rare diseases. https://news.sky.com/story/nhs-to-offer-paid-for-genetic-blueprints-that-predict-health-risks-11618412 3 comments worldnews
- Genetic parasites invaded the mammalian genome more than 100 million years ago transforming the uterus in the ancestors of humans and other mammals from the production of eggs to a nurturing home for developing young. http://www.physorg.com/news/2011-09-invasion-genomic-parasites-triggered-modern.html 32 comments science
- Get your Genome now for several billion doll-- no! a million -- no $5000! -- wait, how about $100! 19.95!! No? Not nineteen?-- $100 then, and in eight hours. http://www.technologyreview.com/biomedicine/22112/ 5 comments technology
- Genetica will migrate 100,000 genomic data profiles to the Oasis Network, allowing users to have full control of their genetic data as part of a partnership with Oasis Labs https://oasis-foundation.medium.com/vietnamese-prime-minister-and-government-support-genetica-and-oasis-labs-partnership-to-enhance-b638a0c8095b 63 comments cryptocurrency
- NIH’s All of Us Research Program releases first genomic dataset of nearly 100,000 whole genome sequences Contributions from diverse participants set to change the landscape of genomics research - Business Announcement - NIH/All of Us Research Program https://www.eurekalert.org/news-releases/946764 2 comments science
- The largest peer-reviewed study of its kind with an international team of 65 scientists studied the genomes of more than 100,000 individuals and found that a genetic predisposition towards higher cognitive ability was associated with longer lifespan. https://www.northwell.edu/about/news/press-releases/feinstein-institute-researchers-identify-new-genes-associated-cognitive-ability 15 comments science
- In 2014 Genia plans on selling gene sequencers capable of sequencing whole human genomes in minutes for $100, 50x cheaper than today ($5000) http://www.biocompare.com/editorial-articles/126329-next-gen-sequencing/ 4 comments technology
- Scientists Sequence Genome of 100,000-Year-Old Polar Bear. Scientists generated & analyzed a paleogenome from an approximately 100,000-year-old polar bear that reveals a massive prehistoric admixture event between polar bears & brown bears, which is evident in the genomes of all living brown bears. http://www.sci-news.com/genetics/polar-bear-paleogenome-10914.html 2 comments science
- More than 40 genes have been linked for the first time to Alzheimer’s disease in a study, paving the way for better diagnosis and treatment. Scientists carried out the biggest research project of its kind looking at the genome (genetic material) of more than 100,000 people with Alzheimer’s. https://www.nature.com/articles/s41588-022-01024-z 2 comments science
- New methods of Genome sequencing (IDB) lead to discoveries of Neanderthal-Human hybrids, back migrating to Africa more than 100,000ya. Predating, the accepted “Horn of Africa” migrations to Europe and Asia 60,000ya. https://www.cell.com/cell/fulltext/S0092-8674(20)30059-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420300593%3Fshowall%3Dtrue 55 comments science
- Scientists unveil 'unified genealogy of modern and ancient humans' | With more than 3,600 individual genome sequences that date back more than 100,000 years, it is largest human family tree ever created. https://www.science.org/doi/10.1126/science.abi8264 27 comments science
- Scientists compare the complete genomes of over 100 organisms (mostly animals), to study how the animal kingdom has evolved at the genetic level & find the origins of major groups of animals, such as the one comprising humans, are linked not to the addition of new genes but to massive gene losses. https://www.inverse.com/science/evolution-that-famous-march-of-progress-image-is-just-wrong 5 comments science
- The critically endangered Grauer's gorilla has recently lost genetic diversity and has experienced an increase in harmful mutations, according to a sequencing of 11 genomes from specimens collected up to 100 years ago, which were compared with genomes from existing gorillas. https://www.cell.com/current-biology/fulltext/s0960-9822(18)31554-9 5 comments science
- By studying the genome of Lonesome George, a 100-year-old giant Galapagos tortoise who died in 2012, scientists say they've found the secrets to his old age. The reptile's genes show signs of protecting the animal from cancer, bolstering its immune system and better regulating metabolism. http://blogs.discovermagazine.com/d-brief/2018/12/03/giant-tortoise-genome-reveals-secrets-to-long-life/#.xaw4bjnkhty 11 comments science
- An international team reveals that human genome could contain up to 20% fewer genes, suggesting that humans may have only 19,000 coding genes, 3,000 fewer than the sum of the three reference annotations of the human genome and a much lower number than the 100,000 predicted just twenty years ago. https://www.cnio.es/ing/publicaciones/an-international-team-led-by-the-cnio-reveals-that-human-genome-could-contain-up-to-20-fewer-genes 19 comments science
- An international team reveals that human genome could contain up to 20% fewer genes, suggesting that humans may have only 19,000 coding genes, 3,000 fewer than the sum of the tree reference annotations of the human genome and a much lower number than the 100,000 predicted just twenty years ago. https://www.cnio.es/ing/publicaciones/an-international-team-led-by-the-cnio-reveals-that-human-genome-could-contain-up-to-20-fewer-genes 4 comments science
- Researchers sequence, analyze genomes of glowing bacteria in the bulbs that hang off heads of anglerfish. There's evidence the symbiotic relationship between the two is still evolving, even though the fish evolved about 100 million years ago. The bacteria are still losing genes, and it’s unclear why http://news.cornell.edu/stories/2018/07/genetics-shed-light-symbiosis-anglerfish-and-glowing-bacteria 6 comments science
- Patients with mutations in the RPE65 gene suffer from blindness. In a new Phase 3 study, clinicians have demonstrated that gene therapy, by injecting over 100 billion viral vector genomes into the eyes of these patients, could substantially improve their ability to perceive light, navigate and read. http://www.sciencedirect.com/science/article/pii/s0140673617318688?via%3Dihub 11 comments science
- The power of big data must be harnessed for medical progress: "clinical data from a single individual will generate 0.4 terabytes of information per lifetime, genomics data around 6 terabytes and additional data, 1,100 terabytes." http://www.nature.com/news/the-power-of-big-data-must-be-harnessed-for-medical-progress-1.21026 3 comments technology
- Britain launches genome database for patients' DNA. Up to 100,000 Britons suffering from cancer and rare diseases are to have their genetic codes fully sequenced and mapped as part of government plans to build a DNA database to boost drug discovery and development. http://www.straitstimes.com/breaking-news/world/story/britain-launches-genome-database-patients-dna-20121210 13 comments worldnews
- In the past 12 months, close to 100 common genetic variants have been linked to major diseases, using a new gene-hunting technique called whole-genome association. http://www.timesonline.co.uk/tol/life_and_style/health/article3682615.ece 2 comments reddit.com